Protein crystallization – is it rocket science?

Protein crystallization – is it rocket science?

Source :

• Drug Discovery Today [ 1359-6446 ] ; 2001.

Descripteurs français

• Wicri :
  • topic : Biochimie, Biotechnologie.

English descriptors

• KwdEn :
  • Biochemistry, Biotechnology, Drug Discovery, Structural Biology, Techniques & Methods, electron density, microgravity, protein crystallisation.
• Teeft :
  • Acta crystallogr, Aqueous solution, Aqueous solutions, Atomic force microscopy, Best data, Biological macromolecules, Biophysical sciences, Bovine insulin, Canadian space agency, Control experiments, Convection, Cryst, Crystal, Crystal growth, Crystal handling, Crystal interface, Crystal lattice, Crystal quality, Crystal size, Crystal surface, Crystalline surface, Crystallization, Crystallization apparatus, Crystallization conditions, Crystallization experiments, Crystallization methods, Crystallogr, Crystallographic community, Crystallography, Crystallography facility, Data collection, Diffraction, Diffraction data, Diffraction resolution, Dynamic control, Electron density maps, European space agency, Experimental conditions, First time, Fundamental factors, Fundamental studies, Growth medium, Growth solution, Higher resolution, Human insulin, Hydrodynamic size, Insulin, Insulin crystals, International space station, Isothermal conditions, July, Larger crystals, Lysozyme, Lysozyme crystal growth, Macromolecular, Macromolecular crystal growth, Macromolecular crystallization, Macromolecular crystallography, Macromolecule, Major impediment, Microgravity, Microgravity crystallization, Microgravity crystallization results, Microgravity environment, Microgravity experiments, Microscopic video, More uniform, Multiple protein batches, Nasa, National aeronautics, National research council, Natural product inhibitor, Nucleation, Overall diffraction quality, Postnucleation phases, Protein, Protein concentration, Protein crystal growth, Protein crystallization, Protein crystals, Protein molecule, Protein molecules, Protein samples, Protein solution, Protein solutions, Protein structures, Report figure, Reservoir solution, Schlieren photograph, Second virial coefficient, Several investigators, Shuttle, Solution components, Sophisticated laboratory, Space administration, Space experiments, Space shuttle, Space shuttle flights, Space station, Spacegrown crystals, Special report, Structural biology, Success rate, Synchrotron radiation, Tetragonal lysozyme crystal, Triglycine sulfate, Triglycine sulfate crystal, Unit gravity, Vapor diffusion, Video observation, Virus crystal growth.

Abstract

• https://api.istex.fr/ark:/67375/6H6-6WL1SVNK-F/fulltext.pdf

Affiliations:

• États-Unis

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